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Research shows that most patients regain 50-75% of lost weight within one year of discontinuation, primarily because appetite hormones like ghrelin rebound to baseline levels

JES is supported by a National Health and Medical Research Council investigator grant

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She holds a masters degree in clinical nutrition from New York University, as well as advanced certifications as a Women's Fitness Specialist and a Behavior Change Specialist

Methods STEP 5 was a DB RCT conducted at 41 sites in Canada, the US and Europe, and randomized 304 patients with overweight or obesity, 1:1, to either semaglutide or placebo