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At 48 weeks, participants in the 12 mg group achieved a mean weight reduction of 24.2% compared to 2.1% for placebo

J Clin Invest , 95 (2), 859873

Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment

Cucurbitacin B exerts significant antidepressant-like effects in a chronic unpredictable mild stress model of depression: involvement of the hippocampal BDNF-TrkB system