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Inhibition of DPP4 activity by synthetic inhibitors, such as those used to treat type 2 diabetes, results in suppression of T cell proliferation in vitro and a decrease in antibody production in vivo

A:Over 10 years

Ginsenoside Rb3 (G-Rb3), one of the major saponins in Panax ginseng , enhances FAO and mitochondrial function via PPAR activation and upregulation of key -oxidation enzymes and Sirtuin 3(SIRT3) (Yang et al., 2022), though standardized dosing and large-scale randomized controlled trials (RCTs) are needed to confirm efficacy

Reduced cysteine storage raises gamma-glutamyl transferase (GGT) in the liver and kidneys, breaking down glutathione (GSH), an antioxidant