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Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders

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Unknown long-term effects, especially for newer agents like retatrutide

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Detoxification support: Aids liver function by facilitating the removal of toxins and harmful substances

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Attenuation of High Glucose-Induced Rat Cardiomyocyte Apoptosis by Exendin-4 via Intervention of HO-1/Nrf-2 and the PI3K/AKT Signaling Pathway

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1 Introduction Recently, the increasing incidence and mortality of cancer have become a major threat to human health ( Ferroptosis is a novel form of iron-dependent programmed cell death, characterized by iron accumulation, lipid peroxidation and antioxidant imbalance, which extremely is distinct from necrosis, apoptosis, and autophagy (Xie et al., 2016)

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