The transcriptional response to chronic stress and glucocorticoid receptor blockade in the hippocampal dentate gyrus
2 GPX family and oxidative stress 2.1 GPX1 Glutathione peroxidase 1 (GPX1) was first identified in 1957 as a red blood cell enzyme that protects hemoglobin from oxidative stress ( 2 O 2 and soluble low-molecular hydroperoxides, but not with more complex lipid hydroperoxides
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Because Fe-S clusters function as essential cofactors for components of the electron transport chain, TCA cycle enzymes, and genome maintenance machinery, their stability depends on a reducing intracellular environment that is maintained, in part, by GSH 203,208
And so I can give you a different example
