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Notably, amyloid deposits in ATTR patients correlate with markers of lipid peroxidation, such as 4hydroxytrans2nonenal (HNE) adducts [35] and oxidative DNA damage indicated by 8hydroxy2deoxyguanosine (8OhdG) [34]

We recorded whether the mouse was able to walk, or not, on the treadmill for 60 s, with gentle prodding as needed

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