Aydin 1 , Frank Te Nijenhuis 2 , Marta Rubiera 3 , Susanne Bonekamp 4 , Ronen R Leker 5 , Satoru Tanioka 1 , Theo van Walsum 2 , Charles Majoie 6 , Wim Van Zwam 7 , Sam Payabvash 8 , Thomas Tourdias 9 , Christian Nolte 10 , Dietmar Frey 1,11 1 CLAIM - Charit Lab for Artificial Intelligence in Medicine, Charit Universittsmedizin Berlin, Germany, Berlin, Germany, 2 Biomedical Imaging Group Rotterdam, Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, 3 Department of Neurology, Vall dHebrn University Hospital, Barcelona, Spain, 4 Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany, 5 Stroke Unit, Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel, 6 Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, Netherlands, 7 Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, Netherlands, 8 Department of Radiology, Columbia University, New York, United States, 9 Department of Neuroradiology, CHU Pellegrin, Bordeaux, France, 10 ent of Neurology with Experimental Neurology and Center for Stroke Research Berlin (CSB), Charit Universittsmedizin Berlin, Berlin, Germany, 11 Department of Neurosurgery, Charit Universittsmedizin Berlin, Berlin, Germany Background and Aims: Modelling of prognosis has the potential to improve treatment decisions and establish precision medicine in ischemic stroke

July 15, 2021
Laboratory studies demonstrated: Enhanced fatty acid oxidation in treated animal models Increased plasma glycerol release (an established index of active lipolysis) Elevated mitochondrial fatty acid oxidation capacity Both energy expenditure and fat oxidation increases even without classical -AR pathways The peptide appears to modulate metabolic flexibility in adipocytes
KPV (Lysine-Proline-Valine) Peptide
Bostan AC, Strick PL