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As a pain killer, it was used for earache and toothache and occasionally as a poultice

Centers for Disease Control and Prevention (CDC) has called vitamin E acetate a "chemical of concern" and recommended not adding it to e-cigarettes or vaping products while the investigation proceeds

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Singapore, which has prohibited e-cigarettes since 2018, has significantly increased penalties for violations starting September 2025, with new laws taking full effect in Q1 2026