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The diverse and dynamic phenotypes of reactive astrocyte reflect their context-dependent heterogeneity and adaptive capacity, which enables structural, molecular and functional adaptations to shifting physiological conditions and pathological insults

Weisberg et al., in 2006 demonstrated that knocking out C-C chemokine receptor type 2 (CCR2), a crucial MCP-1 receptor, shows decreased adipose tissue macrophage recruitment and inflammatory gene expression and further protected against insulin resistance in HFD models [30]

Chen J, Huang L, Zeng L, Jiang Z, Xiong M, Jia ZJ et al (2024) The reference range of lamotrigine in the treatment of epilepsy in children: a systematic review

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