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Notably, the report suggested that semaglutide might improve obesity-associated subclinical neurodegeneration and might promote the regeneration of small corneal nerve fibers, indicating a potential neuroprotective effect during treatment

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CLUH functions as a negative regulator of inflammation in human macrophages and determines ulcerative colitis pathogenesis

db/db mouse, a type 2 diabetic mouse model that mimics the renal fibrotic features of human DKD, has significantly higher levels of renal ANGPTL4 expression, suggesting a potential role for ANGPTL4 in DKD (Mizunuma et al., 2020)