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But the same trial flagged more atrial fibrillation, more blood clots, and, in a follow-up, more broken bones, most of them from ordinary falls, for reasons nobody has fully explained (New England Journal of Medicine, 2024)

Wang CF, Huang LL, Buchenauer H, Han QM, Zhang HC, Kang ZS

Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats

adding genetic clarity helps your provider select the formulation (injection versus oral, Semaglutide versus Tirzepatide, or dual-compound) most likely to succeed