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During the smoking cessation process, the body undergoes adaptation and regulation, which could lead to temporary immune system disruptions and changes in liver metabolic functions, thus having complex effects on viral infections 32

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Thus, apparent reported morphometric findings might be at least partially related to transient changes in blood flow or other physiological signals

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The model has held up over 30 years, almost 10 years beyond the original sample, through changing economic conditions and levels of California tobacco control spending, according to Lightwood