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As an example of just one CBD-drug interaction, CBD can increase the blood concentration of certain blood thinners, an excess of which can cause internal bleeding

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Brioschi S, Wang WL, Peng V, Wang M, Shchukina I, Greenberg ZJ, Bando JK, Jaeger N, Czepielewski RS, Swain A, Mogilenko DA, Beatty WL, Bayguinov P, Fitzpatrick JAJ, Schuettpelz LG, Fronick CC, Smirnov I, Kipnis J, Shapiro VS, Wu GF, Gilfillan S, Cella M, Artyomov MN, Kleinstein SH, Colonna M (2021) Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders