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In utero cigarette exposure was associated with lower birthweight (3,035 490 versus 3,405 598 g, p = 0.005), with linear modeling of the smoking cohort showing a 41 g reduction for every increase of one cigarette smoked per day (95% CI 71 to 11 g, p = 0.010)

As expected, there was variation between individuals, but the CSE effects seem to be consistent, except for the IL6 responses, which is in line with the clinical findings among smokers 31

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