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You should consider scheduling an appointment with a sinus specialist if you experience any of the following: Your symptoms last longer than 10 days without improvement or continue to worsen over time You experience severe facial pain or pressure that doesnt respond to over-the-counter medications You notice thick, discolored nasal discharge (yellow or green) that persists for more than a week You develop a high fever (above 101F) along with your sneezing and nasal symptoms You cant stop sneezing despite trying various remedies You notice blood in your nasal discharge or experience frequent nosebleeds Your symptoms only occur on one side of your nose rather than both sides Youre experiencing breathing difficulties or wheezing along with your sneezing If you find yourself in the middle of a sneeze attack that happens multiple times per day and interferes with your work, sleep, or quality of life, its time to seek professional help

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On the other hand, negative confounding is plausible and would occur if smoking rates are lower among ST users than among nonusers of ST