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[21] But e-cigarette users may "learn" to overcome the unpleasant taste due to elevated aldehyde formation, when the nicotine craving is high enough

Nicotine salt formulations in e-liquids, which buffer pH to 5.0-5.5, enable concentrations up to 50 milligrams per milliliter without throat harshness, a breakthrough that closed the satisfaction gap with combustible cigarettes

Pure cocaine has no distinctive odor

Given this, it is easy to refute any claims that the harmful chemical in a cigarette is the nicotine

The 2025 NYTS survey shows that nearly 90% of youth who use e-cigarettes use flavored varieties, with the most commonly used flavors being fruit (62.1%)