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Delay in diagnosis and treatment of tuberculosisA review

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Tobacco smoking reduces p53, a tumor suppressor gene that is considered the genome guardian. Suppression of T-cell responses by Nicotine and tar is associated with decreased surveillance for tumor cells] reported that heavy smokers accumulate excess iron in hepatocytes which induces fibrosis and favors the development of HCC

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Consider non-nicotine medications The FDA and Health Canada have approved several non-nicotine containing drugs to help smokers quit