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Studies have found evidence showing that nicotine is harmful for health, affecting brain development up to the age of 25

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The organized crime network behind the operation is suspected of large-scale cigarette trafficking with profits estimated at $647,000 per week.[18] Global illicit trade in tobacco is a growing problem, but is considered low-risk, high-reward

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If such mutations are seen in critical regions of important growth control genes, the end-result may be the loss of normal cellular growth control mechanisms, genomic instability, as well as cancer in the long run