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Benzo(e)pyrene, a toxic compound found in cigarette smoke, also causes cell death in human retinal pigment epithelial cells (ARPE-19), and induces apoptosis through the involvement of multiple caspase pathways (27)

The safety profile of varenicline in this study was good and similar to that of previous varenicline trials of smokers in the general population [33, 34]

Smokers with LC were predominantly male, while non-smokers with LC were predominantly female 3 , which was consistent with the results of the present study

A gentle pinch along the body should suffice to assess its consistency and hardness

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