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ruling had opened up an opportunity for such groups as the American Cancer Society to put a whole series of anti-smoking commercials on the air, and in 1970 anti-cigarette messages were occupying some sixty million dollars worth of commercial air time and were causing the tobacco industry serious concern, because they were apparently effective

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The mediation analysis revealed that SII accounted for 87.70% of the total effect, while the average direct effect (ADE) of smoking on mortality, independent of SII, was not statistically significant