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Both nicotine and caffeine, when consumed in moderation, are generally deemed safe for most adults [15]

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Global RYO Tobacco, Roll Your Own Tobacco Products Market, By Region, 2019-2030 (USD Billion) 3

The risks of long-term nicotine use can be fatal as smokers are more likely than nonsmokers to develop: Nicotine can also cause: Dizziness Headaches Anxiety Trouble sleeping Heart disease Stroke lung cancer Asthma The American Lung Association estimates that cigarettes have 600 ingredients

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