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In the Netherlands, UK, and much of Europe, spliffs are often the default way to consume cannabis socially, while American cannabis culture traditionally favors pure joints or other consumption methods

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Center for Tobacco Products: Fact Sheet on Safe Disposal of E-cigarettes and E-liquid Fact sheet with information about how to safely dispose of e-cigarettes/vapes and e-liquid to reduce the negative impact on the environment

The Allergy & Asthma Network and Ann Allergy Asthma provide data on cannabis allergies

But its also possible that it has an effect over time