and (2) when either no other biosimilars have been approved for the same reference product or no other biosimilars with the same reference product report positive ASP data for the given quarter, we are proposing to set the payment limit equal to the sum of the volume-weighted average of the most recent available positive ASP data from a previous quarter plus 6 percent (or 8 percent for a qualifying biosimilar biological) of the amount determined under section 1847A(b)(4) of the Act for the reference biological product for the given quarter

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Karin Jepsen (University of Bonn, Germany), presented research which showed that antimicrobial resistance is on the rise among German patients with severe periodontitis