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Chris Allen, CEO of UK-based consultancy Broughton, called the keynote one of the most significant speeches weve heard in years, marking the FDAs first public acknowledgment of harm reduction as a principle embedded in its regulatory framework in years, while public health expert Cliff Douglas posted on X that the speech was refreshing and potentially groundbreaking, noting Koplows clear articulation of the benefits of switching from cigarettes to alternative products

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They join the World Health Organization (WHO), the US Centers for Disease Control and Prevention, the Food and Drug Administration and the European Society of Cardiology in urging smokers to try to give up the habit, regardless of which smoking method they use

Willis on July 2, 1982, in Winston-Salem, North Carolina