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Loose tobacco used for roll-your-own (RYO) cigarettes is taxed differently and at a lower effective rate per cigarette equivalent

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"Cigarette smoke consists of numerous compounds that are harmful, and it has been linked to a reduction in the thickness of layers in the brain , and to brain lesions, involving areas such as the frontal lobe, which plays a role in voluntary movement and control of thinking, and a decrease in activity in the area of the brain that processes vision," he said