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The remaining differences can also be explained quite simply: for example, the greater need for anemia patients, by the fact that not only is the intrinsic factor switched off, but their ability for passive diffusion is diminished

Similarly, ovarian oxidative stress model mice exhibit inhibition of the Nrf2/HO-1/GPX4 pathway (Niu et al., 2023), suggesting that GPX4 deficiency-induced ferroptosis may contribute to reduced ovarian reserve

Supplements work for some, but injections are more effective for people with absorption issues or low energy levels

They may need to rely on supplements or vitamin B12 injections to maintain adequate levels, and the frequency of supplementation will affect how long the vitamin stays in the body