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Definitive evidence on whether and which metabolites are associated with cancer risk will lead to more opportunities to develop preventive and/or therapeutic interventions against cancers.

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Furthermore, MR studies leverage the random allocation of genetic variation, akin to the design of a randomized controlled trial, thereby strengthening causal inference beyond mere association

Previous studies have made efforts to characterize the oral microbiome in several populations (Kilian et al., 2016

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