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The collected data included important details of the study, such as authors, year of publication, journal name, study title, country of origin, study design, data sources, study duration, total sample size, subject characteristics (such as age and gender), the definition of e-cigarettes usage (current/former use), the definition of the control group (never smoker), the effect size and corresponding 95% confidence interval (95% CI), the diagnostic criteria for COPD (self-report/pulmonary function tests/EHRs), and the way of obtaining smoking history (self-report/urine nicotine test)