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Whether autocrine signaling through the CCL2 receptor protein CCR2 occurs in transformed SV-HUC cells remains to be established, although other groups have reported non-transformed SV-HUC cells to be unresponsive to recombinant CCL2 whereas this chemokine can drive the migration and invasion of BC cells derived from more advanced tumors 62

Wang Q, Wang Y, Zhang Y, et al

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