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This reflects ongoing efforts to balance legacy tobacco sales with growth in newer categories amid regulatory pressures worldwide

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In order to be able to account for the potential impacts of subclinical cerebrovascular disease, we used FLAIR images (checking T 1 - and T 2 -weighted images when necessary) to obtain each subjects Fazekas score, a standardized visual rating scale that provides a measure of white matter hyperintensities (WMH) load