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Benowitz from University of California, San Francisco, and colleagues, compared nicotine metabolism in 88 men and 206 women, and compared the 53 women who used oral contraceptives with the 153 who did not

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Smoking progressively damages cardiovascular health by narrowing arteries, reducing oxygen levels in blood, and increasing clot formation risk

The fact that we are still talking about these brands and are still aware of their influence - even to the point where it infiltrates Kens character arc in the Barbie movie - goes to show how truly impactful this advertising was.