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"This case is a good reminder that melanoma could happen in the oral cavity, but it's a very rare event." Email Bahar Gholipour or follow her @alterwired

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3.6.1.6 Summary In summary, miners subjected to chronic exposure throughout a working lifetime to high-LET radiation show a radiation/tobacco smoke interaction greater than additive and sometimes multiplicative

Retrieved from Verywell Health 4.Dove Press

However, about 5% will eventually develop squamous cell carcinoma (SCC) If there is an associated erythematous appearance ( erythroplakia ), there is a higher risk of dysplasia or cancer (90%) *A separate disorder that is not premalignant is oral hairy leukoplakia , an Epstein-Barr virus-induced lesion that occurs almost entirely in HIV-infected patients The diagnosis of leukoplakia is suspected in patients presenting with a white lesion of the oral mucosa that cannot be wiped off with gauze and that persists after eliminating potential etiologic factors, such as mechanical friction, for a six-week period Excisional biopsy is indicated for any undiagnosed leukoplakia leukoplakia - all should be treated For 23 circumscribed lesions, surgical excision For multiple or large lesions where surgery would cause unacceptable deformity, consider cryosurgery or laser surgery Removal of predisposing habits (alcohol and tobacco) Complete excision is the standard treatment for dysplasia or malignancy After treatment, up to 30% of leukoplakia recurs, and some leukoplakia still transforms into squamous cell carcinoma Oral Hairy Leukoplakia is unlikely to progress to squamous cell carcinoma Treatment with zidovudine, acyclovir, ganciclovir, foscarnet, and topical podophyllin or isotretinoin