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In other words, if a substance causes a symptom in healthy individuals, giving someone a tiny amount of the same substance may cure his or her condition

In addition, nicotine can affect bacterial clearance through the reduction of macrophages due to the activation of 7-nAChR ( Enterobacteriaceae and the phylum Bacteroidetes ( Enterobacteriaceae and Bacteroidetes decreases a few months after smoking cessation, while the abundance of some Firmicutes bacteria increases (1)