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(1) For each applicable period beginning on or after October 1, 2022, the reduced rebate amount for a Part D rebatable drug currently in shortage will be calculated using the following formula: Equation 1 to Paragraph (b)(1) Reduced Total Rebate Amount = the total rebate amount multiplied by (1 minus applicable percent reduction) multiplied by (percentage of time drug was currently in shortage during the applicable period) added to the total rebate amount multiplied by (1 minus percentage of time drug was currently in shortage during the applicable period) (2) For purposes of paragraph (b)(1) of this section, the applicable percent reduction is: (i) For a Part D rebatable drug that is a generic drug or plasma-derived product: (A) 75 percent for the first applicable period such drug is currently in shortage