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The lead SNP at the chr5q34 locus, rs1862416, is annotated to enhancer histone marks in brain (specifically, germinal matrix during fetal development and the developed prefrontal cortex, anterior caudate, and cingulate gyrus tissues) and several other tissues in HaploReg 43
We found that smoke treatment could up-regulate the expression of p21 compared with the control group without smoke (Fig
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Tobacco smoke carries several harmful toxic chemicals that can damage skin cells
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