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An examination of adolescents ranging in age from 12 to 19 found that heritability estimates for initiation of smoking ranged from 36% to 56% across varying samples, with similar heritability estimates for regular smoking ranging from 27% to 52%

Of the studies which measured side effects, none found any serious side effects of using electronic cigarettes for up to two years

28 This RCT found that there may be a moderate cessation benefit when nicotine e-cigarettes with behavioural support and nicotine patch access were compared with nicotine patch and behavioural support alone (46 more per 1000, 95% CI 2 fewer to 200 more

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