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However, their combination with sulfonylureas (SUs) increases the risk of severe hypoglycemia, necessitating careful dose adjustments, especially in older adults and those with impaired renal function [22]

Polysomnographic measurements confirmed shortened sleep onset latency, meaning participants fell asleep faster

To further overcome unsatisfactory performance of ICBs in MM, combination of ICBs with different targeted therapy strategies has been tested in clinical trials

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Effect of angiotensin II on ACTH release in vivo: role of corticotropin-releasing factor