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3.36.1 Biological mechanisms for low-rate smoking posing substantial major health risks One explanation for lack of substantial risk reduction after reduction in smoking is compensation: smokers who cut down on number of cigarettes per day (CPD) tend to take more and deeper puffs from each cigarette, and smoke more of it

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SMP has received consulting fees from Altavant, Theravance, and BMS and received research funding from AZ, BI, and CareDX, unrelated to the content of this manuscript