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The same team found that smoking also increases the risk of bipolar disorder, in another Mendelian randomization study published in September

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When looking at EMS-induced DNA damage, the PARP1 762 variant allele carriers presented an increase of DNA damage in E group comparatively to the wild-type carriers, although not significant, due to small number of variant allele carriers

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In this review, we will summarize related articles and give a glance of possible mechanism between cigarette smoking induced COPD and lung cancer