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Tobacco is intended to be used for recreational purpose, but due to the presence of addictive alkaloids, people get highly addicted to tobacco and its products

1992;145(2 Pt 1):301310

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It should also be noted that the National Academies of Sciences, Engineering, and Medicine in 2018 released a report summarising available evidence regarding the public health consequences of electronic cigarette use.99 That report concluded that there is no available evidence as to whether or not electronic cigarette use is associated with clinical cardiovascular disease outcomes and subclinical atherosclerosis

For estimated APW costs (column [1]), we relied on publicly available literature and reports for as many of the six countries as possible