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The Aircosmeticss (@aircosmeticss) TikTok account (now removed) was of particular concern, researchers note

As would be expected, there was a wide variability of weight change: 16-21% of patients (one in five or six) lost weight throughout the study

156 It has been proposed that oxidative stress can inactivate HDAC2 by means of nitration or carboxylation and that HDAC2 is phosphorylated, ubiquitinated, and degraded as a consequence of cigarette smoke exposure

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