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however, human PK studies were submitted and are more informative ( 4 Discussion and next steps For ethical and scientific reasons, there is a need to use reproducible and human-relevant testing approaches without the use of animals to better understand the potential adverse effects of TNCPs on humans

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Community immunity

Given the observed association between tobacco smoke exposure and early-onset OA in this cross-sectional study, our findings suggest that reducing smoking and environmental nicotine exposure may be beneficial