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Open J Clin Diagn 3:58 Gorska KR, Domagala-Kulawik J, Korcznski P, Nejman-Gryz P, Kosciuch J, Hildebrand K, Chazan R (2008) Comparison of cellular and bichemical markers of airway inflammation in patients with mild -to-moderate asthma and chronic obstructive pulmonary disease: an induced sputum and bronchoalveolar lavage fluid study

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I have been dipping Creek Long Cut Wintergreen since 1996, before then i dipped Skoal...I love the quality and taste of Creek Long Creek Wintergreen, as well as the affordability, and the fact that you get 2 cans in one pack...but I buy it by the case, normally 3 cases a month