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Melatonin Suppresses Inflammation and Blood-brain Barrier Disruption in Rats with Vascular Dementia Possibly by Activating the SIRT1/PGC-1/PPAR Signaling Pathway

Both medications demonstrated blood pressure reductions in clinical trials beyond what weight loss alone would predict

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For example, mitochondrial dysfunction is prevalent in both idiopathic ASD (31) and is associated with Rett syndrome (3234), PTEN mutations (35), Phelan-McDermid syndrome (36), 15q11-q13 duplication syndrome (37, 38), Angelman syndrome (39), Septo-optic dysplasia (40), and Down syndrome (41, 42)