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Research has revealed additional benefits beyond those primary uses but some negative side effects have also emerged

Nov 19, 2024, 14:45 ET The trial achieved both its primary endpoints, with semaglutide 2.4 mg demonstrating statistically significant and superior improvements in liver fibrosis with no worsening of steatohepatitis, as well as resolution of steatohepatitis with no worsening of liver fibrosis in people with MASH compared to placebo

The second concerns endpoints: a program built around biomarker movement needs a clear, pre-specified theory of how that biomarker connects to clinical benefit, and a plan for what a divergence would mean

Regular physical activity not only supports weight loss but also improves overall health, including cardiovascular fitness and mental well-being

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