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Opposite effects of low and high doses of A42 on electrical network and neuronal excitability in the rat prefrontal cortex

The second, semaglutide at the 2.4 mg dose, is the GLP-1 receptor agonist already established for weight management

Its cognition-enhancing effects may be due to an ability to influence the brains levels of noradrenaline, serotonin, and dopamine,4 three neurotransmitters with well-documented relationships to vigilance, attention, learning,5 memory,6 and the motivation toward cognitive effort.7 Meanwhile, its anxiolytic effects appear to be GABAergic (i.e., relating to the neurotransmitter GABA)

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Dosing Guidelines: 100-500mcg 1-3x/day for a 12-week cycle