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Although the FAERS database aids in detecting rare adverse events via spontaneous reporting, its propensity to overestimate unexpected adverse events linked to new therapies makes it inappropriate for comparative analysis of adverse event frequencies among pharmaceuticals

Injections are typically administered subcutaneously

doi: 10.1001/jamanetworkopen.2024.27258 Summary Keywords comparative effectiveness, glycemic control, narrative review, obesity pharmacotherapy, Semaglutide, tirzepatide, weight loss Citation Harbi MH, Ashour AM, Alorfi NM, Aldurdunji MM, Wali SM and Alzahrani YA (2026) Tirzepatide vs

Biochimie, 95 (10), 18111827

The effects of GLP-1 RAs on insulin and glucagon secretion being glucose dependent, there is a considerably low risk of documented hypoglycemia when utilizing these drugs accompanied with a rapid reduction in HbA1c [20]