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MAD has several advantages including that it is safe, effective, can be rapidly initiated, and that its beneficial effects can be observed almost immediately (7)

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Underlying numerical data for Fig 1 graph adjacent to phylogeny

As one trial participant described, With PT-141, you feel good not only sexually aroused, you feel younger and more energetic. Another said it helped the libido and that his wife could tell the difference between sex on Viagra versus sex on PT-141

Aim for a modest caloric deficit of 300-500 calories below maintenance, with protein intake around 0.8-1 gram per pound of body weight