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Combined with adequate protein intake (widely recommended at 1.2-1.6g per kg of body weight during GLP-1 protocols) and resistance training, the higher dose ranges may actually preserve lean mass better than lower doses, because the energy deficit is being met predominantly through fat oxidation rather than muscle catabolism

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More importantly, this work reveals a significant difference between the sulfenylation reagents and organoselenium reagents

Resistance exercise is the most effective intervention against muscle loss during caloric restriction