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This guide walks through the latest clinical evidence, including the 2025 SURMOUNT-5 head-to-head trial, so you can have an informed conversation with your provider

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However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions

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The menopausal transition is associated with a natural decline in estrogen and nitric oxide production, which can impair endothelial function[6] and reduce genital blood flowkey elements in arousal and sexual response